• September 24, 2022

University of Liverpool Confirms a Rise in Adverse Drug Reactions

University of Liverpool Confirms a Rise in Adverse Drug Reactions

Various long-term health issues (referred to as multimorbidity) and the concurrent use of multiple medications have been linked to the tendency, which is referred to as multimorbidity (called polypharmacy).

Researchers from Bangor and Liverpool universities conducted it at Liverpool University Hospitals NHS Foundation Trust. Two doctors examined the medical records of 1187 patients admitted over a month in 2019.

Professor Sir Munir Pirmohamed and colleagues published the initial fundamental paper in the BMJ in 2004. 6.5 percent of all hospitalizations were attributed to adverse medication reactions (ADRs). Among those admitted to the hospital, 16.5 percent had an unfavorable reaction to medication as a cause or a complicating factor.

Five or more regular medications are considered polypharmacy. People with an ADR were found to be taking more medications and suffering from more comorbid diseases than those who did not have an ADR.

Overprescribing, or giving individuals medicines they don’t need or want, can make polypharmacy a hardship for patients, especially if it occurs in the context of overprescribing. Prescription overdoses have increased considerably in the recent quarter-century. According to recent research on over-prescription, ten percent of prescriptions (about 110 million) should not have been provided by the NHS.

This new study shows that the problem is growing and that a whole-systems approach is needed to address the socioeconomic, systemic, and cultural factors that contribute to overprescribing drugs.

Research reveals that adverse drug reactions have a major impact on patients and hospitalizations, said Dr. Rostam Osanlou, an expert in clinical pharmacology. The NHS spends more than $2 billion annually on this and additional efforts to improve patient care and save the NHS money.

A senior clinical lecturer at the University of Liverpool, Dr. Lauren Walker, said patients must report adverse drug reactions to the MHRA using the yellow card system. Patients should inform their healthcare provider of any negative effects they may be experiencing, and they should not stop taking their medication alone.

The new analysis underscores the continued burden inflicted on patients and the NHS by adverse medication responses, said David Weatherall, Chair of Medicine Professor Sir Munir Pirmohamed. Preventing this requires a multi-pronged approach that includes better prescribing education and technological tools. This is in line with the NHS’s long-term goals.

According to the researchers ‘ calculations, ADRs that result in hospitalization cost at least £2 billion a year. To enhance the benefit-risk balance of prescribed drugs and minimize the burden of ADRs on patients and healthcare providers, a coordinated national effort beyond those highlighted in the NHS overprescribing report is required.

News: Source

 
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